Anna Kuzina
Machine learning for medical imaging

Anna Kuzina

ML developer and molecular immunology researcher. 3D segmentation of organs and lesions in clinical CT, and the evaluation protocols that make small-cohort results trustworthy.

Anna Kuzina

Research experience

ML Developer Intern

Jun 2026 — Present
Clinic of Urology, Sechenov University · supervised by Ivan Chernenkiy
  • Reformulating the nested lesion target as multilabel took lesion Dice from 0.00 to 0.37, liver to 0.96.
  • Local iteration time cut from 110 s to 3 s by retuning voxel spacing and patch size.
  • Evaluation moved to class-stratified 5-fold cross-validation; pipeline reproducible end to end on the institute’s GPU cluster.

Research Assistant, Molecular Immunology

Sep 2023 — Present
I.I. Mechnikov Research Institute of Vaccines and Sera · Prof. O.A. Svitich, MD
  • First author on the hormones–HIV-1 entry work: two peer-reviewed papers and prizes at two national conferences.
  • CCR5/CCR8 and TLR2/4/9 expression quantified across multi-donor PBMC panels and three HIV-1 subtypes; expression related to viral load at 3.8×, p = 0.0033.
  • Two further first-author lines: oral mucosal repair after vestibuloplasty, and bacteriophage therapy in a Pseudomonas aeruginosa wound-infection model.

Senior Laboratory Technician

Nov 2020 — Sep 2023
Functional Neurochemistry, P.K. Anokhin Research Institute of Normal Physiology

Apoptosis-regulator gene expression related to spatial-memory performance (Morris water maze); owned the RT-qPCR workflow end to end.

Full methods and detail in the CV.

Peer-reviewed publications

Viruses · 2025 · 17(11), 1512

Gonadocorticoids Have Different Effects on the Expression of Toll-like Receptors When Infected with Various HIV-1 Subtypes

Nosik M., Ryzhov K., Berezhnaya E., Bystritskaya E., Lobach O., Kiseleva I., Kostyuchenko E., Kuzina A., Meremianina E., Kireev D., Svitich O.

doi:10.3390/v17111512
Bulletin of Experimental Biology and Medicine · 2025 · 179(4), 480–484

Effect of Female Sex Hormones on the Expression of CCR5/CCR8 Coreceptor Genes and Viral Replication in HIV-1 Infection

Nosik M.N., Bystritskaya E.P., Ryzhov K.A., Berezhnaya E.V., Lobach O.A., Kiseleva I.A., Kireev D.E., Kuzina A.V., Kostyuchenko E.P., Vasilieva V.E., Zimina A.A., Svitich O.A.

doi:10.47056/0365-9615-2025-179-4-480-484

Selected presentations

Effect of phage therapy on the expression profile of innate immunity factors in an in vivo Pseudomonas aeruginosa wound infection model
New Approaches in Microbiology, Virology, Immunology and Epidemiology, 2026
Oral · first author
Effect of estradiol and progesterone on CCR5/CCR8 coreceptor gene expression in HIV-1 subtype G infection
Lomonosov International Scientific Conference, Fundamental Medicine, 2024
1st place, oral
The role of innate immunity gene expression in oral mucosal repair after vestibuloplasty
Medical Spring International Youth Scientific Forum, 2025
2nd place, oral
Influence of sex hormones on Toll-like receptor expression in cells infected with HIV-1 subtype G
Lomonosov International Scientific Conference, Experimental Research, 2025
Poster · co-author

Posters at the XLVI Scientific Session “Systemic Organisation of Physiological Functions” (2022) and “Current Issues in Developmental Biology” (2021). Ten or more contributions in total, 2021–2026.

Applied ML projects

plaint.com

Adverse-drug-reaction mining from patient narratives. Built backend, frontend and the ML/NLP layer: LDA/NMF topic modelling, transformer classification and rule-based extraction over 800+ reviews. Winning team, BIOMEDTECH.

RoBERTa · PharmBERT · FastAPI

42.doc

Clinician matching by embedding retrieval, with evidence-snippet attribution for every recommendation.

RAG · pgvector

Oncomatrix

Temporal retrieval answering oncology questions against the guideline version in force at the date of the clinical event.

RAG · PostgreSQL

Imaging coursework

Dental pathology detection on panoramic radiographs (mAP@0.5 0.761) and three-class breast ultrasound classification by transfer learning (accuracy 0.87, macro ROC-AUC 0.95).

YOLOv8 · PyTorch · torchvision

Awards & funding

Scholarship of the Government of the Russian Federation
Granted by federal order under a national quota of 4,500 student awards per year
2024/25, 2025/26
Prize Winner, “I am a Professional” All-Russian Student Olympiad
Preventive Medicine track, two consecutive seasons. In 2024/25, 3,838 medals across 185,610 participants (top 2%)
2024–2026
1st place, best oral presentation — Lomonosov International Scientific Conference
Fundamental Medicine. Also 2nd place oral at Medical Spring 2024 and 2025, and 2nd place at the VI Scientific Career Centre Conference, 2022
2024
Winning team, IPHARMA case — BIOMEDTECH championship
Skolkovo × Moscow State University, against 15 teams and 64 participants
2025

Education

I.M. Sechenov First Moscow State Medical University

Sep 2020 — Aug 2026
Specialist Degree in Medical Biochemistry — GPA 5.00/5.00 (highest attainable)

Six-year integrated programme; the Russian Specialist Diploma is a single-tier qualification benchmarked at integrated Master’s / MSc level (EQF 7). Institute of Biodesign and Complex Systems Modeling.

School 21 × Sechenov University Joint Campus

Sep 2024 — Jun 2025
Artificial Intelligence in Medicine — peer-to-peer engineering programme

Admitted through a competitive selection intensive (3:1); algorithms, systems and relational databases in Bash, SQL/PostgreSQL and Python, followed by a deep learning specialisation in PyTorch.

Sechenov University — Professional Retraining

Sep 2023 — Aug 2026
Medical Data Analyst · Translator/Interpreter in Professional Communication (English)

Skills

Machine learning
PyTorchMONAIscikit-learnOpenCV3D segmentationCNNsTransfer learningObject detectionCross-validation designEvaluation under class imbalance
Programming & infrastructure
PythonSQLBashSLURMSingularityDockerGitLab CIMLflowTensorBoardFastAPIPostgreSQLGitLinux
Quantitative biology & statistics
pandasNumPySciPyGraphPad PRISMDifferential expressionNon-parametric inferenceVariance decompositionSmall-cohort design
Laboratory
RT-qPCRRNA extractioncDNA synthesisGel electrophoresisIn vivo infection models
Languages
Russian — nativeEnglish — IELTS 7.5, professional translator qualificationGerman — A1